The Ophthalmology Unit,  Universiti Malaysia Sarawak (UNIMAS), Kuching, Sarawak.

The Ophthalmology Department, Sarawak General Hospital, Kuching, Sarawak, East Malaysia.



Limbal stem cell deficiency

Photo by Professor Chua Chung Nen

This 48 year-old woman is the sister of the previous case. She also has cleft palate and recurrent red eyes. Examination revealed superior limbal stem cell deficiency in the superior cornea. The cornea shows neovascularization and calcification. She is on long term low dose steroid to reduce the progression of the neovascularization. Autologous stem stem cell graft from the inferior cornea with amniotic membrane cover is planned to reverse the corneal changes.


Left superior corneal neovascularization with lipid keratopathy and calcification.


Right superior limbal stem cell deficiency with corneal neovascularization and calcification.

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